The aim of the study was to determine the optimal dose of papain in feed to increase growth and survival rate of vannamei shrimp (Litopenaeus vannamei) in aquaponic recirculation systems. Culture vessel in the form of tarp of 50 x 50 x 50 centimeters of 12 tarp with stocking density of 20 shrimp/m3. This research was using experimental method by completely random design (RAL) one factor with fo…