This research was conducted on May 1 - June 10, 2019, at the Laboratory of Aquaculture Technology, Faculty of Fisheries and Marine, University of Riau. This study aims to determine the best dosage of Papain enzymes mixed in commercial feed to see the growth and survival of Cachama(Colossoma macropomum). The research container used was a 60x40x40 cm3 aquarium with 12 aquariums with a stocking de…