Profil Mutasi Gen Reverse Transcriptase Virus Hepatitis B Pada Penderita Hepa…

Hepatitis B is a liver disease characterized by hepatocellular injury caused by hepatitis B virus (HBV) infection. Reverse transcriptase is part of the HBV polymerase enzyme which lacks proofreading activity and is therefore prone to error during replication. Mutations in reverse transcriptase gene are associated with the emergence of resistance to nucleos(t)ide analogue antiviral treatment…