Hypercholesterolemia is complication in type 2 diabetes. Alpha lipoic acid (ALA) can reduce total cholesterol by modulating cholesterol synthesis pathway and reduced cholesterol biosynthesis genes expression. The goal of this research was to investigate prohibition of hypercholesterolemia in type 2 diabetes rat by ALA. Fifteen adult male wistar rats (2-3 months 200-250 g body weight) were segreā¦