ABSTRACT Waste diapers contain cellulose pulp that can be used as a substrate in the production of cellulase. In this research, the baby diapers was degradate with biodegradable method use bactery S-16 and S-22 with solid fermentation until 10, 20, 30, 40 and 50 days. The activity of an enzyme extract rough is determine with Nelson Somogiy method’s, organic carbon (TOC) using Gravimetric met…