ABSTRACT Chalcone is secondary metabolites, which include flavonoid that have some biological activities such as anticancer, anti-inflammatory and antimicrobial. Generally chalcone analogues can be synthesized via Claisen-schmidt condensation of an aromatic ketones with aromatic aldehydes. In this study, the analogue of chalcone (E)-4-(3-(4'-methoxyphenyl)-3-oxoprop-1-en-1-yl))benzaldehyde (SF…