Rhizophora sp. is one of the mangrove plant which potentially for antibacterial compound, because it has an alkaloids, saponins, flavonoids and tannins. This research purpose was to know the proper dose of Rhizophora sp. leaves extract in healing the MAS disease (Motile Aeromonas Septicaemia), which can be seen through the leukocytes differentiation of Pangasius hypophthalmus. The method in thi…