CD Skripsi

Isolasi Dan Uji Toksisitas Senyawa Metabolit Sekunder Dari Fraksi Diklorometana Kulit Batang Pulai Alstonia SCHOLARIS

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SUMMARY
Alstonia scholaris or commonly known as the pulai is a plant that is often found in the Southeast Asian region. This plant belongs to the Apocynaceae family. It has the potential as a medicinal ingredient for various diseases because of the presence of several secondary metabolites. This study aims to isolate and characterize alkaloid secondary metabolites from the dichloromethane fraction of the stem bark of the A. scholaris plant and to analyze the toxicity test of the dichloromethane fraction from the stem bark of the A. scholaris plant. Phytochemical tests from the bark of the A. scholaris plant showed the presence of secondary metabolites including alkaloids, phenolics and terpenoids. The extraction process was carried out using the maceration method with methanol solvent and followed by a fractionation process using the acid-base partition method to obtain a thick dichloromethane extract. Separation of components in the sample was carried out using flash chromatography, gel chromatography and preparative thin layer chromatography. Characterization with the UV-Vis spectrum obtained a maximum wavelength at 338 nm indicated the presence of conjugated double bonds. Toxicity testing was conducted using the brine shrimp lethality test (BSLT) method. The results of the toxicity test on the dichloromethane fraction of A. scholaris stem bark obtained an LC50 value higher than 1000 ppm. Therefore the dicholoromethane was considered as non-toxic extract.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

1903112208

Penerbit

Pekanbaru : Universitas Riau - FMIPA - Kimia., 2023

Deskripsi Fisik

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Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

1903112208

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KIMIA

Info Detail Spesifik

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Pernyataan Tanggungjawab

TETHI

Versi lain/terkait

Lampiran Berkas

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