CD Skripsi

Uji Potensi Jamur Phellinus Noxius Brb11 Dan Lentinus Sp Brb12 Untuk Degradasi Kloramfenikol

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Chloramphenicol is a broad-spectrum antibiotic with mechanism of action that inhibits protein synthesis and bacteriostatic. The overuse of chloramphenicol produces residues in the environment and cause bacterial resistance. Chloramphenicol can be biologically degraded using white rot fungi. The purpose of this study was to examine the ability of the white rot fungi Phellinus noxius BRB11 and Lentinus sp BRB12 to degrade chloramphenicol. In this study, the growth of fungi after the addition of chloramphenicol was analyzed both on fungi biomass and the activity of the laccase and manganese peroxidase (MnP) enzymes. The effectiveness of degraded chloramphenicol was also tested against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Salmonella typhimurium bacteria. The results showed that the growth rate of Phellinus noxius BRB11 and Lentinus sp BRB 12 was slower along with high concentration of chloramphenicol added. In Phellinus noxius BRB11, the MnP enzyme plays a greater role in degrading chloramphenicol, whereas in Lentinus sp BRB12 the laccase enzyme plays a more significant role in degrading chloramphenicol. The best degradation results occurred in the Lentinus sp BRB12 14 days incubation with a concentration of 500 ppm which was 95.11%. This study shows that Phellinus noxius BRB11 and Lentinus sp BRB12 can produce enzymes that have the potential to be used to degrade chloramphenicol.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

1803110486

Penerbit

Pekanbaru : Universitas Riau - FMIPA - Kimia., 2023

Deskripsi Fisik

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Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

1803110486

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KIMIA

Info Detail Spesifik

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Pernyataan Tanggungjawab

PUJA

Versi lain/terkait

Lampiran Berkas

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