CD Skripsi

Isolasi Dan Uji Toksisitas Metabolit Sekunder Bakteri Endofit Dari Tumbuhan Leban (Vitex Pubescens Vahl)

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The leban plant (Vitex pubescens Vahl) is one of the medicinal plants of the Vitex genus and the Lamiaceae family. Lebanese plants have been widely used by the community as traditional medicine to treat several diseases and have been reported to contain active compounds betulinic acid, 14-deoxyandrographolida, and andrographolida. To minimize the use of plants as a source of biologically active compounds, research is directed towards the use of endophytic bacteria that are known to produce secondary metabolites similar to their hosts. This study aims to isolate endophytic bacteria from the stem bark and leaves of leban plants, macroscopic and microscopic characteristics, and conduct toxicity tests using the brine shrimp lethal test (BSLT) method. A total of 16 isolates of endophytic bacteria from the stem bark and 4 isolates from the leaves of bean plants located in the Riau University environment have been successfully isolated. Based on Gram staining, 1 isolate of Gram-negative endophytic bacteria and 19 isolates of Gram-positive endophytic bacteria were obtained. The results of toxicity tests using the BSLT method against Artemia salina test animals gave the lowest LC50 value in isolate D2B1 of 19.99 µg/mL which indicated a very toxic nature. A total of 11 other isolates were found to be toxic, while isolates K1B1, K1B9, K1B11 and D2B1 were not toxic. The results of this study show the potential of endophytic bacteria from the stem bark and leaves of bean plants as a source of compounds with anticancer potential.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

2003111264

Penerbit

Pekanbaru : Universitas Riau – FMIPA - Kimia., 2024

Deskripsi Fisik

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Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

2003111264

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KIMIA

Info Detail Spesifik

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Pernyataan Tanggungjawab

Mutia

Versi lain/terkait

Lampiran Berkas

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