Image of perbandingan efektivitas antara deksmedetomidin dengan fentanil sebagai adjuvan pada anestesi spinal terhadap hemodinamik, analgesia dan mual muntah pascaoperasi pasien histerektomi transvagina
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perbandingan efektivitas antara deksmedetomidin dengan fentanil sebagai adjuvan pada anestesi spinal terhadap hemodinamik, analgesia dan mual muntah pascaoperasi pasien histerektomi transvagina

Uterine prolapse is a common medical condition in geriatric women, with a prevalence of 30-50% in those aged 50 and above in Indonesia. One of the common treatments for uterine prolapse is transvaginal hysterectomy, which can be performed under general anesthesia or spinal anesthesia. This study aims to compare the effects of the adjuvans Dexmedetomidine and Fentanyl on spinal anesthesia with hyperbaric bupivacaine in transvaginal hysterectomy procedures for uterine prolapse patients, focusing on hemodynamics, postoperative analgesia, and the occurrence of Postoperative Nausea and Vomiting (PONV). The study uses a clinical trial design with a cross-sectional method, involving 32 patients divided into two groups: 16 patients receiving 10 μg of Dexmedetomidine and 16 patients receiving 25 μg of Fentanyl as spinal adjuvans. The analysis results show that both adjuvans have a similar effect on hemodynamic parameters, with significant differences found in diastolic blood pressure at induction (p=0.012) and Mean Arterial Pressure (MAP) at induction (p=0.014), where Dexmedetomidine was more effective in maintaining blood pressure. Postoperative analgesia was also similar, but the incidence of PONV was lower in the Dexmedetomidine group (25%) compared to the Fentanyl group (50%), although this difference was not statistically significant (p=0.144). This study provides insight into the effectiveness of Dexmedetomidine as an adjuvan in spinal anesthesia for uterine prolapse patients, with the potential for better hemodynamic stability, reduced PONV incidence, and longer postoperative analgesia compared to Fentanyl.
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Keyword : Dexmedetomidine, Fentanyl, Postoperative analgesia, Postoperative nausea and vomiting (PONV), Spinal anesthesia, Uterine prolapse.

Ketersediaan
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Perpustakaan Universitas Riau 2010247297
2010247297
Tersedia
Informasi Detail
Judul Seri
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No. Panggil
2010247297
Penerbit
Pekanbaru : Universitas Riau – PASCA – DOKTER SPESIALIS ANASTESI DAN TERAPI INTENSIF.,
Deskripsi Fisik
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Bahasa
Indonesia
ISBN/ISSN
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Klasifikasi
2010247297
Tipe Isi
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Tipe Media
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Tipe Pembawa
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Edisi
-
Subjek
Spesialis Anastesi dan Terapi Intensif
Info Detail Spesifik
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Pernyataan Tanggungjawab
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Tidak tersedia versi lain

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