CD Skripsi
Gambaran Klinis Dan Laboratorium Pasien Talasemia Yang Mengalami Transfusi Berulang Di Rsud Arifin Achmad Provinsi Riau Tahun 2018-2024
Thalassemia is a genetic disorder characterized by impaired synthesis of hemoglobin globin chains, so that patients often require repeated blood transfusions. Continuous blood transfusions can cause complications such as alloimmunization and iron overload. This study aims to determine the clinical and laboratory features of thalassemia patients who underwent repeated transfusions at Arifin Achmad Hospital, Pekanbaru in 2018–2024. This study used a descriptive design with a cross-sectional approach, involving 70 thalassemia patients who met the inclusion criteria. Data were obtained from medical records and analyzed univariately. The results showed that the majority of patients were aged ≤18 years (61.5%) and male (51.5%). The most common clinical complaint was paleness (81.3%), followed by weakness (35.3%) and growth disorders (10%). Laboratory examination showed that most patients had anemia (98.5%), with an average hemoglobin value of 7.68 g/dL, platelets 190,000/μL, and leukocytes 7,200/μL. The Mentzer index indicated a high probability of thalassemia. Transfusion reactions and incompatible crossmatch results were also found in some patients. These results indicate the importance of regular clinical and laboratory monitoring to prevent further complications.
Keywords : Clinical Features of Thalassemia, Laboratory Features of Thalassemia, Homoglobin, Mentzer Index, Repeated Transfusion
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