CD Skripsi

Gambaran Penggunaan Antibiotik Definitif Berdasarkan Hasil Kultur Dan Sensitivitas Antibiotik Pada Pasien Sepsis Di Intensive Care Unit Rsud Arifin Achmad Provinsi Riau Tahun 2023-2024

---

Sepsis is a medical emergency with high morbidity and mortality, demanding optimal management, including the adjustment of definitive antibiotics based on culture and sensitivity results. This retrospective descriptive study aims to provide an overview of culture results and the pattern of definitive antibiotic therapy use in 57 sepsis patients treated at the Intensive Care Unit (ICU) of RSUD Arifin Achmad Provinsi Riau during the 2023–2024 period. The method utilized involved the collection of secondary data through total sampling from medical records. The results indicated that 45 patients (78,9%) had positive cultures, with 30 patients (52,6%) was male. The most frequent age group was 45–64 years (38,6%), and the most common comorbidity was diabetes mellitus (26,3%). The most commonly used specimen type is sputum (59.6%) with the most common location of infection is the respiratory tract (54.4%). Culture results were predominantly comprised of Gram- negative bacteria, with the most isolated pathogens was Klebsiella pneumoniae (33,3%) and Acinetobacter baumanii (22,2%). Antibiotics showing the highest sensitivity were amikacin (80,5%) and meropenem (65,9%). The most frequently used definitive antibiotic was meropenem (62,22%), and the overall concordance rate of definitive antibiotic administration based on culture results reached 30 patients (66,7%). The mortality rate was recorded as high, affecting 28 patients (62,22%). The study concludes that Gram-negative bacteria are the dominant cause of sepsis in the ICU of RSUD Arifin Achmad. Amikacin demonstrated the highest sensitivity level, while meropenem was the most frequently used definitive antibiotic, and the mortality rate among sepsis patients remains considerably high.


Key words: Culture, definitive antibiotics, ICU, sepsis, sensitivity.

---

Ketersediaan

Informasi Detail

Judul Seri

-

No. Panggil

2208156358

Penerbit

Pekanbaru : Universitas Riau – Fakultas Kedokteran - Pendidikan Kedokteran., 2025

Deskripsi Fisik

-

Bahasa

Indonesia

ISBN/ISSN

-

Klasifikasi

2208156358

Tipe Isi

-

Tipe Media

-

Tipe Pembawa

-

Edisi

-

Subjek

PENDIDIKAN KEDOKTERAN

Info Detail Spesifik

-

Pernyataan Tanggungjawab

Vina

Versi lain/terkait

Lampiran Berkas

Komentar

---

Anda harus masuk sebelum memberikan komentar