CD Skripsi

Analisis Ekspresi Gen Chek2 Pada Kanker Endometrium

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Endometrial cancer is a gynecological malignancy with an incidence rate that continues to increase annually. This indicates the importance of further understanding endometrial cancer, especially regarding its pathogenesis. One gene that plays a crucial role in its pathogenesis is the CHEK2 gene. Checkpoint kinase 2 (CHEK2) is a gene that plays a crucial role in the DNA damage response mechanism that regulates cell cycle arrest and DNA repair. However, the role of the CHEK2 gene in endometrial cancer has not been widely studied. This study aims to analyze the relationship between CHEK2 gene expression and the clinical profile of endometrial cancer patients. This study used a cross-sectional design with CHEK2 gene expression data and clinical profiles of endometrial cancer patients from The Cancer Genome Atlas (TCGA) database obtained from the UCSC Xena Browser and cBioPortal. Based on the analysis results, CHEK2 gene expression was found to be significantly higher in endometrial cancer tissue compared to normal endometrial tissue (p

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

2208112441

Penerbit

Pekanbaru : Universitas Riau – Fakultas Kedokteran - Pendidikan Kedokteran., 2025

Deskripsi Fisik

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Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

2208112441

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

PENDIDIKAN KEDOKTERAN

Info Detail Spesifik

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Pernyataan Tanggungjawab

Vina

Versi lain/terkait

Lampiran Berkas

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