CD Skripsi
Hubungan Tingkat Kepatuhan Farmakoterapi Dengan Capaian Kriteria Pengendalian Diabetes Melitus Tipe 2 Di Dua Rumah Sakit Swasta Pekanbaru
Pharmacotherapy adherence is pivotal for managing Type 2 Diabetes Mellitus. This cross-sectional study aimed to analyze the association between pharmacotherapy adherence levels and the achievement of various control criteria among 75 patients at two private hospitals in Pekanbaru. Pharmacotherapy adherence was measured using the MMAS-8 questionnaire. Clinical data were collected from medical records and direct measurements. Results showed that 52% of respondents had high adherence, a rate considered suboptimal. Glycemic control criteria (HbA1c) was largely uncontrolled in most respondents (70.7%). Most respondents also failed to achieve non-glycemic control criteria, including LDL (92%), BMI (66.7%), and waist circumference (74.7%). Conversely, the majority of respondents achieved controlled targets for triglycerides (54.7%), SBP (64%), and DBP (80%). Spearman’s correlation test indicated a significant association between levels of pharmacotherapy adherence and achievement of HbA1c (p=0.001, rho=0.502), SBP (p=0.015, rho=0.28), DBP (p=0.028,
rho=0.254), triglycerides (p=0.03, rho=0.251), BMI (p=0.003, rho=0.34), and waist circumference (p=0.029, rho=0.253). Notably, no significant association was found between adherence and LDL-C control (p=0.112, rho=0.185). This study concludes that pharmacotherapy adherence is significantly associated with glycemic and most non-glycemic control criteria in T2DM patients, except for LDL-
C. These findings highlight the critical need for strategies to enhance adherence to improve clinical outcomes.
Keywords: Control criteria, MMAS-8, pharmacotherapy adherence, private hospital, type 2 diabetes mellitus.
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