CD Skripsi

Analisis Hubungan Ekspresi Gen Poly (Adp-Ribose) Polymerase 1 (Parp1) Dengan Profil Pasien Kanker Endometrium

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Endometrial cancer is one of the most common gynecological malignancies, originating from the epithelial lining of the uterus, with its incidence and mortality rates increasing over the past few decades. In Indonesia, endometrial cancer ranks 14th among all cancer cases in 2020. This study aimed to analyze the expression of the PARP1 gene in endometrial cancer and its association with patient profiles and survival outcomes. This study utilized publicly available data from The Cancer Genome Atlas (TCGA), accessed via the UCSC Xena Browser and CBioPortal. Most patients were aged 61-70 years (34,50%). The majority were in early stage disease (stages I-II) (71,93%), with 28,07% in advanced stages (III-IV). Based on differentiation, 59,63% of cases were poorly differentiated (grade III). Histologically, type 1 tumors predominated (75,05%). In molecular classification, CNL was found to be the most dominant with a percentage of 16.51%. PARP1 expression was significantly associated with endometrial cancer tissue (p

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

2208112453

Penerbit

Pekanbaru : Universitas Riau – Fakultas Kedokteran - Pendidikan Kedokteran., 2025

Deskripsi Fisik

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Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

2208112453

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

PENDIDIKAN KEDOKTERAN

Info Detail Spesifik

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Pernyataan Tanggungjawab

Vina

Versi lain/terkait

Lampiran Berkas

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