CD Skripsi

Uji In-Vitro Hidroksiapatit Berpori Menggunakan Larutan Simulated Body Fluid (Sbf)

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Porous hydroxyapatite has high biocompatibility, osteoconductivity, and resorbable properties. One technique for making porous hydroxyapatite is the starch consolidation method. The purpose of this study was to carry out an in-vitro test of porous ceramics formed by the starch consolidation method using Simulated Body Fluid (SBF) solution and to determine the effect of starch mass addition and the duration of porous HA immersion on the formation of apatite layers through porous ceramic in-vitro tests using SBF solution. This research was conducted by mixing 4, 6 and 8 grams of potato starch with 12 grams of HA, 35 mL aquadest. The slurry is stirred at 150 rpm for 3 hours. The formed slurry is put into a mold and dried using an oven at 80°C for 24 hours and 120°C for 8 hours. Green bodies that have been dried are burned using a furnace at 600°C and continued by a sintering process at 1250°C. Subsequently, the samples were characterized using XRD analysis for crystallinity, morphology using SEM, Ca/P composition using SEM-EDX, shrinkage, density, porosity, compressive strength, and AAS for calcium concentration in SBF solution. Depreciation of the sample in this study amounted to 55.92-64.29%, porosity 28.50-37.26%, density 1.94-2.29%, compressive strength of 1.09-2.33 MPa, concentration of Ca2 + on day the 7th 41.16-43.21 ppm, the 14th day 37.61-39.88 ppm, the 21st day 35.78-39.49 ppm and the 28th day 35.78-39.49 ppm, the crystallinity of the sample before SWB 68.38-73.56% after the SBF 73.75-77, 19%, average pore size of 30-300 µm and sample Ca / P ratio of 1.82-2.69. Making porous HA produced as a bone implant mechanically and biologically can be applied as a bone implant due to apatite growth.

Keywords : Hydroxyapatite, Simulated Body Fluid (SBF), In-Vitro Test

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

07 02. 119 (0213)

Penerbit

Pekanbaru : Universitas Riau – Fakultas Teknik – Teknik Kimia., 2019

Deskripsi Fisik

v, 52 hlm.; ill.; 29 cm

Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

07 02. 119 (0213)

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KIMIA

Info Detail Spesifik

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Pernyataan Tanggungjawab

DAUS

Versi lain/terkait

Lampiran Berkas

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