Lumbar Spinal Stenosis (LSS) is caused by narrowing of the vertebral canal due to degenerative changes in the intervertebral discs, facet joints, and ligamentum flavum, leading to clinical symptoms such as low back pain and neurogenic claudication resulting from nerve or vascular compression. This study aims to identify the general profile and functional status of postoperative Lumbar Spinal St…
Type 2 diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia that leads to endothelial dysfunction and accelerates atherosclerosis. Vascular Cell Adhesion Molecule-1 (VCAM-1) plays a key role in this process. Inulin, a prebiotic fiber from dahlia tubers, has anti-inflammatory properties through inhibition of the NF-κB pathway. This experimental study aimed to evaluat…
Diabetes mellitus is a chronic disease with a high prevalence in the working area of Puskesmas Tualang. Traditional medicine is often considered safe and associated with minimal side effects. This quantitative descriptive study aims to identify the patterns of traditional medicine use among 71 respondents with diabetes mellitus. Data were collected using a questionnaire covering the types of pl…
Adolescence is a critical period for nutritional needs, as it is characterized by significant physical, psychological, and social growth and development. One of the main features of this phase in females is the onset of menstruation. Nutritional status plays an important role in menstrual patterns, both through adequate nutrition for endometrial regeneration and its influence on reproductive ho…
Adolescence is a vulnerable period to nutritional status disorders due to the increased need for nutrients to sustain rapid growth and development. An imbalance in nutritional status during this period can lead to malnutrition, which can affect growth, development, and overall health in adolescent. This research aims to describe the nutritional status of adolescent girls at SMAN Pintar Kuantan …
Thoracic cavity malignancy is a malignancy that occurs in the thorax which includes lung cancer (primary), mediastinal tumor, mesothelioma, tumor metastasis in the lungs and chest wall tumors. Lung tumor condition in which cells grow uncontrollably in the lungs, mediastinal tumor is abnormal condition characterized by the presence of a mass in the thoracic compartment that separates the right a…
Intraocular pressure is the pressure within the eyeball that depends on the balance between the production and drainage of aqueous humor, and it may be influenced by systemic factors such as blood pressure. This study aimed to determine the relationship between systolic and diastolic blood pressure and intraocular pressure among patients at the Ophthalmology Clinic of a private hospital in Peka…
Body Mass Index (BMI) is an anthropometric parameter commonly used to assess nutritional status and is associated with various systemic conditions, including intraocular pressure (IOP) elevation. Increased IOP is a major risk factor for glaucoma, the second leading cause of blindness worldwide. However, the relationship between BMI and IOP remains inconsistent across studies. This study aimed t…
Thalassemia is a genetic disorder characterized by impaired synthesis of hemoglobin globin chains, so that patients often require repeated blood transfusions. Continuous blood transfusions can cause complications such as alloimmunization and iron overload. This study aims to determine the clinical and laboratory features of thalassemia patients who underwent repeated transfusions at Arifin Achm…
Domestic violence (KDRT) does not only affect women, but can also be experienced by men. However, cases often go unreported due to social stigma and gender bias. This study aims to describe the profile of cases of physical domestic violence in men examined at Bhayangkara Hospital Pekanbaru in 2020–2024. The study used a retrospective descriptive design with secondary data from Visum et Repert…
Endometrial cancer is a malignancy originating from the epithelial lining of the uterus. Previous studies have reported that dysregulation of the DNA mismatch repair (MMR) system occurs in more than 30% of endometrial cancer cases, with Muts Homolog 2 (MSH2) gene become the MMR gene with the highest mutation rate. The high mutation frequency and the crucial role of the MSH2 gene in the early st…
Lumbar spinal stenosis (LSS) is a condition of narrowing of the spinal canal in the lumbar region that causes cauda equina syndrome. Surgery aims to restore patient’s function and quality of life. This study aims to determine the clinical outcomes of LSS patients after surgery at Arifin Achmad General Hospital Riau Province using the EQ-5D-5L questionnaire. A single-arm retrospective cohort s…
Metabolic dysfunction-associated steatotic liver disease (MASLD), characterized by the accumulation of triglycerides >5% in hepatocytes. In Indonesia, the prevalence reaches 51%. Dietary interventions and functional foods are widely studied approaches as prevention strategies. Puduong, a traditional fermented food made from Pangasius sp., contains protein hydrolysates rich in bioactive peptides…
During the COVID-19 pandemic, post-mortem examinations required major procedural adjustments to ensure staff safety while maintaining the quality of forensic services. This mixed-methods study aimed to describe the characteristics of post-mortem cases handled at the Forensic Medicine and Health Division of the Riau Regional Police from 2020 to 2022, and to explore the experiences and challenges…
Mesenchymal stem cells (MSCs) are multipotent stem cells with the ability to proliferate, differentiate, and immunomodulate. Mesenchymal stem cells produce biological coumpounds such as growth factors, cytokines, and chemokines, which have high therapeutic potential for various diseases. This study was motivated due to the high zoonotic potential and ethical concerns associated with the use of …
Central post stroke pain (CPSP) is a common yet often underdiagnosed complication of stroke that markedly affects survivors’ quality of life. This study aimed to determine the incidence and describe the clinical and pain characteristics of patients with CPSP at Arifin Achmad General Hospital, Riau Province, during 2023–2025. A descriptive cross-sectional design was applied involving 270 str…
Central post-stroke pain (CPSP) is a chronic neurological complication that significantly affects the quality of life of stroke survivors. It results from damage to central sensory pathways such as the thalamus, brainstem, and sensory cortex. This study aimed to describe the lesion locations in patients with CPSP at Arifin Achmad General Hospital, Riau Province, during the 2023–2025 period. T…
Endometrial cancer is a malignancy from the epithelial lining of the uterus and ranks as the sixth most common cancer among women worldwide. DNA damage plays an important role in carcinogenesis, especially in endometrial cancer, thereby requiring DNA repair mechanisms in which the X-ray Repair Cross-Complementing 1 (XRCC1) gene takes a pivotal role in maintaining genomic stability through the b…
Adenomyosis is a benign gynecological disorder characterized by the presence of endometrial glands and stroma within the myometrium, frequently associated with infertility. Reduced endometrial receptivity in adenomyosis has been linked to the downregulation of key implantation markers, including HOXA10. Curcumin was known to exert anti-inflammatory effects primarily through inhibition of the NF…
In the context of life, quality of life is an important aspect that must be maintained in order to live well. This quality of life is particularly influential among patients with hypertension, and to maintain it, they are required to engage in physical activity to help regulate blood pressure and promote calorie burning in the body. This study was conducted at the Internal Medicine Clinic of Ar…