ABSTRACT Fatty alcohol is a derivative of vegetable fats and animal oils, and is a non-oil and gas export commodity that is needed by various industries such as perfumes, cosmetics, pharmaceuticals, food and beverages. demand for alcohol is increasing every year. The import of alcohol has been carried out, but the domestic demand for alcohol has not been met. This has led to the establishment …
Pyrazoline and pyrazole are heterocyclic compounds containing two nitrogen atoms and possess bioactivity such as tyrosinase inhibitor, antidiabetic and anticancer. Pyrazoline and pyrazole derivatives of 3,4-dimethoxybenzaldehyde and 3-bromoacetophenone were synthesized through one-pot synthesis and followed by an oxidative aromatization reaction. Pyrazoline compound were purified by recrys…
Kampar River is a source of water that is widely used as raw clean water by the Kampar community. However, the quality of Kampar River water is in the category of unsuitable for use and consumption due to the disposal of industrial waste, resident activities, agriculture and fisheries. Therefore, it is necessary to carry out a water treatment process to improve the water quality, one of whi…
Hyperpigmentation is a disorder of skin pigment that commonly occurs due to an increase in the process of melanogenesis, which causes changes in skin colour to appear dark. Pyrazoline and pyrazole are azole compounds with a five-ring heterocyclic nitrogen atom. Pyrazoline and pyrazole derivatives of 4- chloroacetophenone and 3,4-dimethoxybenzaldehyde were successfully shynthesized through …
Laccase (EC 1.10.3.2, p-diphenol: oxygen oxidoreductase) is a multicopper enzyme (containing 4 copper ions) which is one of the extracellular enzymes that are widely used in the process of lignin degradation. Laccase is classified as an oxidoreductase enzyme capable of oxidizing both aromatic and non aromatic compounds. Laccase enzyme can be found by fungi. One of the fungi that can produce…
The seeds of the jackfruit are one part of the jackfruit that is currently underutilized. Because of the high carbohydrate material in the form of cellulose, several research have attempted to employ jackfruit seeds as an adsorbent. In this study, HNO3 activated jackfruit seeds were modified with the addition of Ca-alginate as methylene blue dye adsorben to enhance absorption. The percentag…
Bacterial isolates named LBKURCC419, LBKURCC423 and LBKURCC424 are natural forest soil bacteria isolated using tetracycline and amoxicillin media from the Giam Siak Kecil Bukit Batu Biosphere Reserve, Riau Province. Bacteria from the natural environment need to be characterized to determine the species, the level of resistance to tetracyclines and amoxicillin, the gene coding for resistance…
The Mimosa pudica is a South American and Central American plant that is commonly found in Indonesia. M. pudica is used as a herbal medicine in Indonesia to treat a variety of diseases. However, the toxicity of this plant has not been thoroughly investigated. Therefore, it is necessary to isolate secondary metabolites and analyzed for their toxicity, as well as extracts. Isolation was acco…
Bruguiera gymnorrhiza is an alternative plant that contains very high bioactive compounds. These bioactive compounds include steroids, terpenoids, saponins, flavonoids, alkaloids and tannins. The purpose of this study was to isolate secondary metabolites and to determine toxicity test by BSLT (Brine Shrimp Lethality Test) method. Leave extraction was carried out using ethanol and then frac…
Pyridazinone is oxo-pyridazine derivative compound that has broad bioactivity, such as an analgesic, anti-inflammatory, antidiabetic, antihypertensive and anticancer. For further development of pyridazinone compounds, in this study, pyridazinone compound substituted benzenesulfonyl have been synthesized and tested their activity as antidiabetic because the target molecule has a hydrophilic …
Mangroves are plants that thrive in coastal areas that have very high potential for bioactive compounds, one of the type of mangrove is Bruguiera gymnorrhiza L. The purpose of this study was the isolation of secondary metabolites and toxicity tests using the BSLT (Brine Shrimp Lethality Test) method. Mangrove leaves were extracted by maceration method using ethanol and fractionated with n-…
This development research aims to develop a LKPD based on the MEA Model on the subject of valid ion balance and pH of saline solution. This research is a development research (R&D) which refers to the 4D stage, but this research only reaches the Development stage. The research instruments used were validation sheets and user response questionnaires. The assessment on the validation sheet is giv…
Talang Mamak is one of proto Malay tribe in Indragiri Hulu Regency, Riau Province. This tribe has local wisdom in the use of plants. As a native tribe they have long history of using plants as medicine, including antidiabetic medicines. Therefore, a scientific investigation on their local wisdom is needed. The objectives of research are: 1) To analyze the antioxidant and α-glucosidase inhibito…
The research that has been done is the Application of Problem Based Learning Model to Improve Concept Understanding and Confidence in Chemical Bonds Learning Materials in class X MIA 1 SMA Negeri 13 Pekanbaru. This research is motivated by the condition of the learning model in the field which is only centered on the teacher (teacher center) so that students do not play an active role in t…
v SUMMARY Diabetes mellitus is a chronic disease with impaired metabolism of carbohydrates, fats and proteins caused by decreased sensitivity and insulin secretion. Pyridazinone is an aromatic ring compound with a six-chain ring structure consisting of four carbon atoms, one oxygen atom and two nitrogen atoms which has various biological activities, one of which is antidiabetic. This research…
SUMMARY Methylene blue is an organic dye that is widely used in various industries such as textiles, paints, plastics, paper and pharmaceuticals. Excessive use of methylene blue and untreated methylene blue waste will cause negative impact for organism and the environment. This study aim to determine the efficiency of methylene blue removal using silver nanoparticle resulted using kepok banana…
SUMMARY Stenochlaena palustris is a species of the genus Stenochlaena that grows in swampy are as and around palm trees, where it frequently forms dense thickets and spreads to cover the ground. Numerous species in this genus have been reported to be antioxidants and antibacterial agents. The purpose of this study is to isolate secondary metabolites from ethyl acetate extract and to evaluate a…
ABSTRACT Laccase Trichoderma asperellum LBKURCC1 an oxidoreductase enzyme with the ability to oxidize various phenolic groups using oxygen as an electron acceptor. Laccase activity can be affected by pH and temperature. In this study, the determination of fractionated laccase activity was investigated in order to obtain higher laccase activity than crude extract activity. Determination of lacc…
SUMMARY Chalcones are composed of two benzene rings connected by a carbon α,β- unsaturated carbonyl structure and has various bioactivity, such as antibacterial, anticancer, antioxidant and inhibitor tyrosinase. For the further development of chalcone compounds, this research has carried out the synthesis of chalcone derivatives and the determination of their activity as a tyrosinase inh…
SUMMARY Rubber seed shells (Hevea brasiliensis) contain fiber and various carbon compounds such a cellulose, hemicellulose, and lignin which are potentially used as adsorbents. In this study, rubber seed shell was carbonized at 500°C for 15 minutes and activated with H3PO4 activator. Various concentrations to find the best conditions of activator H3PO4 are 5; 10; 15%. Activated charcoal produ…