Mesenchymal stem cells (MSCs) have great potential in regenerative therapy, but conventional culture using fetal bovine serum (FBS) poses biological and ethical risks, making human platelet lysate (HPL) a safer alternative. This study aims to compare the expression of interleukin-8 (IL-8) and transforming growth factor-β (TGF-β) genes in MSCs cultured using HPL and FBS supplementation. This e…