Efek Inhibitor Proteasom Terhadap Kadar Kolesterol Total Pada Tikus Model Ate…

Hypercholesterolemia is an important factor in the formation of atherosclerosis. Previous research has shown that proteasome inhibitors can reduce the enzyme 3-hydroxy-3-methylglutaryl-coenzyme a synthase (HMG-CoA synthase) mRNA levels which plays a role in cholesterol synthesis. Objective of this study was to analyze the effect of proteasome inhibitor on total cholesterol levels of atheroscler…