viii ABSTRACT Theuseofantibioticsforinfectionstreatmentinthelongtermmaycausebacteria becomeresistant.Explorationofmicroorganismscapabletoproduceantimicrobial compoundshavewidelybeenreported.Oneofwhichisactinomycetes,agrampositivebacteriathatproducevarioussecondarymetabolites. Thepurposeofthis studywastotestandselecttheabilityof20isolatesofactinomycetes(14isolates from therhizosphereofthe…