Analisis Ekspresi Gen Muts Homolog 2 Pada Kanker Endometrium

Endometrial cancer is a malignancy originating from the epithelial lining of the uterus. Previous studies have reported that dysregulation of the DNA mismatch repair (MMR) system occurs in more than 30% of endometrial cancer cases, with Muts Homolog 2 (MSH2) gene become the MMR gene with the highest mutation rate. The high mutation frequency and the crucial role of the MSH2 gene in the early st…