The purpose of this research was to compare the resistence of Lactobacillus casei subsp. casei R-68 andLactobacillus casei Shirota to various types and dosage of antibiotics and to comparethe antimicrobial activity of Lactobacillus casei subsp. casei R-68 andLactobacillus casei Shirota against pathogenic bacteria (Staphylococcus aureus, Listeria monocytogenes, Salmonella typhi andEscherichia co…