The Siak River experienced lead (Pb) heavy metal pollution in January 2024 ranging from 0.072 - 0.113 mg/L. Very high Pb levels affect the structure of fish organs, especially the kidneys. This study aims to determine the Pb levels in the waters of the Siak River and changes in the macroscopic and microscopic structure of the kidney organs of the catfish Hemibagrus nemurus (Valenciennes, 1840).…