Ditapis dengan
efek antiinflamasi sapropterin terhadap nitric oxide synthase 3, cox-2, il-10…
Hemorrhoids are anorectal disorders characterized by venous dilation and mucosal inflammation. Recent genomic analyses identify nitric oxide synthase-3 (NOS3) as a key risk gene; sapropterin—an FDA-approved 6-R-tetrahydrobiopterin analog for phenylketonuria—is predicted to down-regulate this pathway. Objective: To evaluate the anti-inflammatory effect of sapropterin on NOS3, cyclo-oxygenas…
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- 2110247752
pengaruh prakondisi vitamin d3 terhadap viabilitas, antioksidan dan apoptosis…
Mesenchymal stem cells (MSCs) are well known for their significant therapeutic potential due to several key biological characteristics. However, MSCs have a limited lifespan during in vitro expansion. This limitation is primarily due to the accumulation of reactive oxygen species (ROS), which triggers oxidative stress and can potentially damage biomolecules within MSCs. The objective of this st…
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hubungan persentase metilasi dna dan ekspresi Mrna gen mesoderm spesific tran…
Male infertility is a significant reproductive health issue often associated with sperm quality. One approach to understanding its molecular mechanism is by exploring epigenetic regulation, particularly DNA methylation and gene expression. MEST is an imprinted gene essential for spermatogenesis and has been implicated in infertility, especially in oligozoospermia. Methods: This case contro…
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- 2110247734
hubungan tingkat metilasi dna dan ekspresi Mrna gen h19 pada pasien oligozoos…
Oligozoospermia, occurs in 34.14% of male infertility cases, define as sperm concentration counted less than 15 million sperm/mL/ejaculation. One of the factor that affects sperm concentration is epigenetic factors, including DNA methylation. We hypotized that sperm concentration is affected by the DNA methylation of H19 gene, a significant gene in fetal growth and development, especially in th…
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- 2110247810
Efek Kombinasi Hipoksia dan Interferon-ℽ terhadap Viabilitas, Migrasi dan E…
Background: Mesenchymal stem cells (MSCs) have great potential for therapy due to their self-renewal, differentiation and immunoregulatory capacities. The proliferative and functional activity of MSCs as well as its immunomodulatory properties can be impaired as a result of oxidative stress-induced senescence during long-term culture of MSCs. Modification of MSCs culture is very important to im…
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- 2110247771
Efek Prakondisi Vitamin D terhadap Karakteristik Biologis dan Ekspresi Tumor …
VITRIYANNA MUTIARA YUHENDRI. NIM. 2110247804. The Effect of Vitamin D Preconditioning on Biological Characteristics and Expression of Tumor Necrosis Factor-α, Interleukin-6, Vascular Endothelial Growth Factor in Mesenchymal Stem Cells. supervised by Arfianti and Ismawati. Background: Mesenchymal stem cells (MSCs) have great potential in regenerative medicine applications. Vitamin D has immuno…
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- 2110247804
Efek Anti Inflamasi Metformin Melalui Perubahan Cyclooxygenase-2 (COX-2) dan …
NURUL AZIZAH, Student ID: 2210246766, The Anti-Inflammatory Effect of Metformin Through Modulation of Cyclooxygenase-2 (COX-2) and Interleukin-10 (IL-10) in a Hemorrhoid Rat Model, supervised by Dr. Darmawi M.Biomed., PhD, and Dr. M. Yulis Hamidy, M.Kes, M.Pd.Ked., Sp.K.K.L.P. Background: Hemorrhoids are a medical condition characterized by inflammation and dilation of blood vessels around the…
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- 2210246766
Analisis Efek Antiinflamasi Metformin Melalui Perubahan Ekspresi Tumor Necro…
Hemorrhoids are a condition characterized by the dilation of venous blood vessels in the anorectal region, involving inflammation, thrombosis, and bleeding. Anti-inflammatory treatments are crucial in preventing the progression of hemorrhoids. Metformin, primarily used as an antihyperglycemic drug, also has anti-inflammatory properties. Its use in patients with type 2 diabetes shows potential i…
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- 2210246767
Uji mekanisme kerja antibakteri Turunan diterpen kuinon pada bakteri Gram pos…
Introduction: Diterpene quinone-derived compounds are proven to have antibacterial activity. However, their mechanism of action is unknown. This study aims to determine the mechanism of antibacterial action of a diterpene quinone derivatives (67DOR, 6O7AR) on S. aureus and E. coli through in vitro and in silico assays. Methods: This study is a laboratory experimental through in vitro and in si…
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